💊 Anticoagulation Synthesizer

CHA₂DS₂-VASc, HAS-BLED & Renal Dosing Calculator

Patient Information

Age (years) 75

Sex

Weight (kg) 70

Serum Creatinine (mg/dL) 1.2

CHA₂DS₂-VASc Score

Congestive Heart Failure +1 Hypertension +1 Diabetes +1 Stroke/TIA/Thromboembolism +2 Vascular Disease (MI, PAD, aortic plaque) +1

HAS-BLED Score

Hypertension (uncontrolled, >160 systolic) +1 Abnormal Renal Function (Cr >2.3 or dialysis) +1 Abnormal Liver Function (cirrhosis, bili >2x, AST/ALT >3x) +1 Stroke History +1 Bleeding History or Predisposition +1 Labile INR (if on warfarin) +1 Elderly (>65) or Drugs/Alcohol +1

Risk Assessment & Recommendations

0

CHA₂DS₂-VASc Score

Low Risk

0

HAS-BLED Score

Low Risk

-- mL/min

Creatinine Clearance (Cockcroft-Gault)

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💡 Clinical Synthesis

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📋 Anticoagulation Options

📊 Quick Reference

CHA₂DS₂-VASc Risk

0	0.2% per year
1	0.6% per year
2	2.2% per year
3	3.2% per year
4	4.8% per year
5	7.2% per year
≥6	>9.0% per year

HAS-BLED Risk

0	0.9% per year
1	3.4% per year
2	4.1% per year
3	5.8% per year
4	8.9% per year
≥5	>9.0% per year

DOAC Renal Dosing

Apixaban: 2.5mg BID if 2 of: age ≥80, weight ≤60kg, Cr ≥1.5

Rivaroxaban: 15mg daily if CrCl 15-50

Edoxaban: 30mg daily if CrCl 15-50

Dabigatran: Avoid if CrCl <30